Adsorption, retention and biologic activity of proteins adsorbed on gas discharge treated surfaces

  • Hoffman A
  • Kiaei D
  • Safranj A
 et al. 
  • 4


    Mendeley users who have this article in their library.
  • 3


    Citations of this article.


We have observed that proteins adsorb very tenaciously to polymer surfaces that have been treated with certain gases in a gas discharge. These gases include tetrachoroethylene (TFE) and tetrachloroethylene (TCE). We have studied adsorption of plasma proteins, antibodies, antigens and enzymes. In this article we present results on the adsorption, retention and biologic activity of (a) albumin as a passivating surface, (b) malaria and schistosomiasis antibodies in an immunoassay and (c) horseradish peroxidase (HRP) as a model enzyme biosensor. In some cases, the protein adsorbed to the treated surface retains greater activity and/or greater stability when compared to the untreated control surface. We also discuss the possible mechanism(s) of these interesting and unusual effects. © 1992.

Get free article suggestions today

Mendeley saves you time finding and organizing research

Sign up here
Already have an account ?Sign in

Find this document


  • A. S. Hoffman

  • D. Kiaei

  • A. Safranj

  • J. P. Chen

  • A. Johnstona

  • T. A. Horbett

Cite this document

Choose a citation style from the tabs below

Save time finding and organizing research with Mendeley

Sign up for free