A review of publications relating to the allergies of the dental pulp is presented. The pulp-especially when inflamed-contains antigens, lymphocytes, plasmocytes, IgG, IgM, IgA, and IgE antibodies, mast cells, histamine, and possibly C3. However, no antibody-mediated allergy (hypersensitivity) of the pulp has yet been demonstrated. On the other hand, two types of cell-mediated allergy-the graft-rejection reaction and contact hypersensitivity-have been reported, as well as autoimmunity. © 1978.
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