Analytical techniques in dissolution testing and bioavailability studies

  • Munson J
  • 2

    Readers

    Mendeley users who have this article in their library.
  • 6

    Citations

    Citations of this article.

Abstract

The rate and extent of absorption of a drug into the bloodstream is an important quality characteristic of a dosage form. In vivo bioavailability and in vitro dissolution studies are important in the development and ultimately in the quality control of a dosage form. The integrity of these tests is dependent on the analytical methods used. The advent of very potent drugs used in low dosage and the development of novel drug delivery systems require that the most sophisticated methods are used. This paper surveys recent trends in analytical advances that are useful in dissolution and bioavailability testing and suggests some future directions. © 1987.

Author-supplied keywords

  • Dissolution testing
  • bioavailability
  • immunochemical techniques.
  • stable isotopes

Get free article suggestions today

Mendeley saves you time finding and organizing research

Sign up here
Already have an account ?Sign in

Find this document

Authors

  • James W. Munson

Cite this document

Choose a citation style from the tabs below

Save time finding and organizing research with Mendeley

Sign up for free