Antimutagens reduce ofloxacin-induced bleaching in Euglena gracilis

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Abstract

The genotoxic effect of ofloxacin was significantly decreased by standard antimutagens (sodium selenite, ascorbic acid, butylated hydroxyanisole and butylated hydroxytoluene) in the unicellular flagellate Euglena gracilis. The antiofloxacin activity of sodium selenite was also documented by a bacterial test in which the repair-proficient strain Salmonella typhimurium TA102 was used.

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Ebringer, L., Dobias, J., Krajčovič, J., Polónyi, J., Križková, L., & Lahitová, N. (1996). Antimutagens reduce ofloxacin-induced bleaching in Euglena gracilis. Mutation Research - Environmental Mutagenesis and Related Subjects, 359(2), 85–93. https://doi.org/10.1016/S0165-1161(96)90255-1

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