Application of sulfur ylide mediated epoxidations in the asymmetric synthesis of β-hydroxy-δ-lactones. Synthesis of a mevinic acid analogue and (+)-prelactone B

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Abstract

Catalytic and stoichiometric asymmetric sulfur ylide reactions were employed to prepare alkyl-aryl epoxide intermediates in a convergent manner. These epoxides were utilized in efficient syntheses of the mevinic acid analogue 1 and prelactone B. Graphical abstract. © 2004 Elsevier Ltd. All rights reserved.

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Aggarwal, V. K., Bae, I., & Lee, H. Y. (2004). Application of sulfur ylide mediated epoxidations in the asymmetric synthesis of β-hydroxy-δ-lactones. Synthesis of a mevinic acid analogue and (+)-prelactone B. In Tetrahedron (Vol. 60, pp. 9725–9733). https://doi.org/10.1016/j.tet.2004.07.044

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