Application of sulfur ylide mediated epoxidations in the asymmetric synthesis of β-hydroxy-δ-lactones. Synthesis of a mevinic acid analogue and (+)-prelactone B

  • Aggarwal V
  • Bae I
  • Lee H
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Catalytic and stoichiometric asymmetric sulfur ylide reactions were employed to prepare alkyl-aryl epoxide intermediates in a convergent manner. These epoxides were utilized in efficient syntheses of the mevinic acid analogue 1 and prelactone B. Graphical abstract. © 2004 Elsevier Ltd. All rights reserved.

Author-supplied keywords

  • Epoxides
  • Mevinic acid
  • Sulfur ylide

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  • Varinder K. Aggarwal

  • Imhyuck Bae

  • Hee Yoon Lee

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