An approach to oxazolidin-2-ones from the Baylis-Hillman adducts. Formal synthesis of a chloramphenicol derivative

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Abstract

In this communication we describe a straightforward and diastereoselective approach to prepare functionalised oxazolidin-2-ones from Baylis-Hillman adducts. A stereoselective synthesis of a highly substituted vicinal aminoalcohol and a formal synthesis of a chloramphenicol derivative are also described. © 2002 Elsevier Science Ltd. All rights reserved.

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Coelho, F., & Rossi, R. C. (2002). An approach to oxazolidin-2-ones from the Baylis-Hillman adducts. Formal synthesis of a chloramphenicol derivative. Tetrahedron Letters, 43(15), 2797–2800. https://doi.org/10.1016/S0040-4039(02)00351-9

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