Ascertainment of variations in the biological half-lives of bromide and sodium ions in the rat by in vivo gamma-ray measurement of 82Br and 24Na radionuclides

  • Pavelka S
  • Vobecký M
  • Babický A
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Abstract

With the aid of in vivo whole-body counting of the rats (administered simultaneously with the radionuclides82Br and24Na) by high-resolution gamma-ray spectrometry, we extended the applicability of our experimentally proved hypothesis that the biological half-life of bromide depends on the magnitude of sodium intake rather than on the intake of chloride, as was generally assumed. Variations in the biological half-life of bromide, as a substitute for sodium, were investigated in animals situated in very different physiological states, as regards their metabolic activity. © 2009 Elsevier Ltd. All rights reserved.

Author-supplied keywords

  • Biological half-life
  • Bromide
  • Gamma-ray spectrometry
  • Radionuclide
  • Sodium

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Authors

  • S. Pavelka

  • M. Vobecký

  • A. Babický

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