Asymmetric aldol reactions employing a cyclic sulfamide chiral auxiliary

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Abstract

A titanium enolate derived from (3S,4S)-2,5-dipropionyl-3,4-diphenyl-1,2,5-thiadiazolidine 1,1-dioxide 3 reacts with aldehydes to give syn aldols with high stereoselection (>95:5). © 1992.

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Han Ahn, K., Jin Yoo, D., & Sook Kim, J. (1992). Asymmetric aldol reactions employing a cyclic sulfamide chiral auxiliary. Tetrahedron Letters, 33(44), 6661–6664. https://doi.org/10.1016/S0040-4039(00)61012-2

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