Carbamate linkers as latent N-methylamines in solid phase synthesis

  • Ho C
  • Kukla M
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Abstract

A new linker strategy for solid phase synthesis has been developed. It utilizes LAH reduction of a carbamate connection to Wang resin which results in N-methylamines, a useful functionality in medicinal chemistry.

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Authors

  • Chih Y. Ho

  • Michael J. Kukla

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