Catalytic oxidative carbonylation of aliphatic secondary amines to tetrasubstituted ureas

  • McCusker J
  • Qian F
  • McElwee-White L
  • 5

    Readers

    Mendeley users who have this article in their library.
  • 38

    Citations

    Citations of this article.

Abstract

Secondary amines can be catalytically carbonylated to symmetrical tetrasubstituted ureas using W(CO)6as the catalyst, I2as the oxidant, and CO as the carbonyl source. Preparation of the corresponding tetrasubstituted ureas from the aliphatic secondary amines HNR2(R = C2H5, n-Bu, i-Pr, PhCH2) and HNRR' (R,R' = -(CH2)4-; -(CH2)5-; PhCH2, CH3) was achieved in moderate yields. Aromatic secondary amines are unreactive. (C) 2000 Elsevier Science B.V.

Author-supplied keywords

  • Amine
  • Metal carbonyl
  • Oxidative carbonylation
  • Tetrasubstituted urea
  • Tungsten

Get free article suggestions today

Mendeley saves you time finding and organizing research

Sign up here
Already have an account ?Sign in

Find this document

Authors

  • Jennifer E. McCusker

  • Fang Qian

  • Lisa McElwee-White

Cite this document

Choose a citation style from the tabs below

Save time finding and organizing research with Mendeley

Sign up for free