The CD95(APO-1/Fas)/CD95L system

  • Krammer P
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Abstract

The CD95 system is one of the best studied death systems and plays an essential role in the immune system, particularly in deletion of peripheral T-cells and in homeostasis of the liver. Here genetic defects in the CD95 system are discussed as well as recent findings of the CD95 signalling pathway. Copyright (C) 1998 Elsevier Science Ireland Ltd. All rights reserved.

Author-supplied keywords

  • Apoptosis
  • CD95(APO-1/Fas)
  • Signaling in apoptosis

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Authors

  • Peter H. Krammer

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