Cloning of a cDNA encoding ovine interleukin-3

  • McInnes C
  • Logan M
  • Haig D
 et al. 
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Abstract

A cDNA encoding the ovine hematopoietic growth factor interleukin-3 (IL-3), has been cloned. A 560-bp cDNA, containing the entire protein coding region, was amplified from activated mesenteric lymph node cells. The cDNA was found to share 58% nucleotide identity with hIL-3 and 48% identity with mIL-3. The predicted ovine amino-acid sequence shares 36 and 30% identity, respectively, with the corresponding human and murine proteins. © 1994.

Author-supplied keywords

  • Recombinant DNA
  • hematopoiesis
  • nucleotide sequence

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