Comparative study of SCE induction and cytostatic effects by homo-azasteroidal esters of N,N-bis(2-chloroethyl)aminobenzoic acid in human lymphocytes

8Citations
Citations of this article
4Readers
Mendeley users who have this article in their library.
Get full text

Abstract

The effect of homo-azasteroidal esters of benzoic acid mustard isomers and the 4-methyl derivatives, which have steroidal lactams as a biological basis, on cytogenetic damage was studied. Twenty compounds were comparatively studied, on a molar basis, as regards their ability to induce sister-chromatid exchanges (SCEs) and cell division delays. A correlation between potency for SCE induction, effectiveness in cell division delay and previously established antitumor activity of these compounds was observed. © 1995.

Cite

CITATION STYLE

APA

Mourelatos, D., Mylonaki, E., Papageorgiou, A., Boutis, L., Paradelis, A., Anastasiou, A., & Catsoulacos, P. (1995). Comparative study of SCE induction and cytostatic effects by homo-azasteroidal esters of N,N-bis(2-chloroethyl)aminobenzoic acid in human lymphocytes. Mutation Research Letters, 346(3), 129–133. https://doi.org/10.1016/0165-7992(95)90044-6

Register to see more suggestions

Mendeley helps you to discover research relevant for your work.

Already have an account?

Save time finding and organizing research with Mendeley

Sign up for free