Crystalline erabutoxin c

  • Preston H
  • Kay J
  • Sato A
 et al. 
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Abstract

Erabutoxin c, the minor neurotoxic component from the venom of the sea snake Laticauda semifasciata has been crystallized. Two orthorhombic forms are found-space group P212121and cell dimensions a = 55·8 ± 0·1 A, b = 53·9 ± 0·1 A, c = 41·4 ± 0·1 A and a = 56·2 ± 0·1 A, b = 55·4 ± 0·1 A, c = 38·5 ± 0·1 A. There are two molecules in both asymmetric units. A new form of erabutoxin b has recently been isolated which crystallizes in P212121and appears to be isomorphous with one of the erabutoxin c forms. The cell dimensions are a = 55·7 ± 0·2 A, b = 53·8 ± 0·2 A, c = 41·5 ± 0·2 A. The relationship between the two erabutoxin c orthorhombic forms and the most common erabutoxin a and b orthorhombic form has not yet been established. © 1975.

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Authors

  • Hugh S. Preston

  • Jack Kay

  • Atsushi Sato

  • Barbara W. Low

  • Nobuo Tamiya

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