Crystallization-induced dynamic resolution (CIDR) and its application to the synthesis of unnatural N-substituted amino acids derived from aroylacrylic acids

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Abstract

A highly stereoselective conjugate addition of chiral amino alcohols affords a simple and inexpensive access to a wide variety of N-functionalized homophenylalanine derivatives. Limitations and conditions for application of CIDR to this system were studied. © 2001 Elsevier Science Ltd.

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Kolarovic, A., Berkeš, D., Baran, P., & Povazanec, F. (2001). Crystallization-induced dynamic resolution (CIDR) and its application to the synthesis of unnatural N-substituted amino acids derived from aroylacrylic acids. Tetrahedron Letters, 42(13), 2579–2582. https://doi.org/10.1016/S0040-4039(01)00221-0

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