A thin-layer chromatography (TLC) method is described that can be used to detect benzolyecgonine (BE), a metabolite of cocaine, in human urine. It is a two-part procedure that can be integrated intoa rapid screening program for drug abuse. The first part of the method utilizes two TLC solvent systems to identify a variety of drugs, including BE. The second part is specific for the cocaine metabolite and can be used as a confirmation method. The procedure is sensitive to3-4 μ/ml of BE in urine. © 1977.
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