17Citations
Citations of this article
7Readers
Mendeley users who have this article in their library.
Get full text

Abstract

New adsorptive anodic differential pulse stripping voltammetry method for the direct determination of morphine at trace levels in human plasma of addicts is proposed. The procedure involves an adsorptive accumulation of morphine on a HMDE, followed by oxidation of adsorbed morphine by voltammetry scan using differential pulse modulation. The optimum conditions for the analysis of morphine are pH 10.5, Eaccof -100 mV (vs. Ag/AgCl), and taccof 120 s. The peak current is proportional to the concentration of morphine, and a linear calibration graph is obtained at 0.01-3.10 μg mL-1. A relative standard deviation of 1.06% (n = 5) was obtained, and the limit of detection was 3 ng mL-1. The capability of the method for the analysis of real samples was evaluated by the determination of morphine in spiked human plasma and addicts human plasma with satisfactory results. © 2007 Ali Niazi.

Cite

CITATION STYLE

APA

Niazi, A., & Yazdanipour, A. (2008). Determination of trace amounts of morphine in human plasma by anodic adsorptive stripping differential pulse voltammetry. Chinese Chemical Letters, 19(4), 465–468. https://doi.org/10.1016/j.cclet.2007.12.036

Register to see more suggestions

Mendeley helps you to discover research relevant for your work.

Already have an account?

Save time finding and organizing research with Mendeley

Sign up for free