Effect of moderate physical exercise on plasma and tissue levels of insulin-like growth factor-1 in adult rats

  • De Rezende Gomes M
  • Santana De Oliveira Pires I
  • Alves De Castro I
 et al. 
  • 4

    Readers

    Mendeley users who have this article in their library.
  • 13

    Citations

    Citations of this article.

Abstract

The aim of the present study was to evaluate the influence of moderate physical exercise on muscle, liver, and plasma insulin-like growth factor-1 (IGF-1) levels and to analyze certain protein and carbohydrate metabolism patterns related to this physiological state. Adult male rats were subjected to physical exercise consisting of swimming for a period of 6 weeks. The animals were divided into two groups, a trained (T) and a sedentary (S) group, with both groups receiving a 12% casein diet. The following parameters were analyzed: body weight, food intake, muscle and liver weight, plasma IGF-1, glucose, insulin, urea and creatinine, muscle protein, glycogen, and muscle and liver IGF-1. Group T showed lower body weight, food intake, and glucose and insulin levels than group S. The other parameters did not differ between groups. These results suggest that moderate physical exercise does not alter IGF-1 levels and therefore cannot be considered a regulating factor of IGF-1 under these experimental conditions. © 2004 Elsevier Inc. All rights reserved.

Author-supplied keywords

  • Exercise
  • IGF-1
  • Protein metabolism

Get free article suggestions today

Mendeley saves you time finding and organizing research

Sign up here
Already have an account ?Sign in

Find this document

Authors

  • Mariana De Rezende Gomes

  • Ivanir Santana De Oliveira Pires

  • Inar Alves De Castro

  • Julio Tirapegui

Cite this document

Choose a citation style from the tabs below

Save time finding and organizing research with Mendeley

Sign up for free