The effect of pH on the production of pertussis toxin by Bordetella pertussis

  • Licari P
  • Winberry L
  • Swartz R
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Abstract

The production of pertussis toxin by Bordetella pertussis was increased by controlling the pH at 7.0 through the addition of sulfuric acid. The more commonly used hydrochloric acid and Tris buffer were observed to be detrimental to toxin yields. © 1991.

Author-supplied keywords

  • Bordetella pertussis
  • Pertussin toxin
  • pH control

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Authors

  • Peter Licari

  • Larry Winberry

  • Randall Swartz

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