1. 1. During growth of Tetrahymena pyriformis there is a gradual decline of oxygen consumption and ATP synthesis by the cells. 2. 2. Spectral determination of the mitochondrial cytochromes indicates an increase in cytochromes b and c and a decrease in cytochrome oxidase associated with the respiratory and energy changes. 3. 3. Glyconeogenesis, an important metabolic function in Tetrahymena, is most active during oxygen limitation and diminished respiration. 4. 4. These observations suggest, though do not prove, a possible regulation of glyconeogenests in Tetrahymena at the level of electron transport. © 1971.
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