Effects of Himanthalia elongata on the central nervous system of mice

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Abstract

The effects of a Himanthalia elongata extract were studied on the CNS of mice. A rich protein solution obtained from the seaweed was assayed for myorelaxant, anticonvulsant and analgesic activity and for its effects on spontaneous locomotor activity, amphetamine-induced hypermotility, exploratory behaviour, barbiturate-induced sleep, and body temperature. Very significant reductions in spontaneous motor activity, hypermotility and exploratory behaviour were found. The extract prolonged barbiturateinduced sleep and postponed pentylenetetrazol-induced death. Weak myorelaxant, hypothermic and analgesic effects were also observed, showing that H. elongata can depress the CNS. © 1990.

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Anca, J. M., Lamela, M., Cadavid, I., & Calleja, J. M. (1990). Effects of Himanthalia elongata on the central nervous system of mice. Journal of Ethnopharmacology, 29(2), 225–231. https://doi.org/10.1016/0378-8741(90)90059-3

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