Effects of nitrous oxide exposure on Met-enkephalin levels in discrete areas of rat brain

  • Morris B
  • Livingston A
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Abstract

Rat were exposed to 80% nitrous oxide in oxygen for 1 and 18 h. Met-enkephalin levels in the dorsal raphé, medial thalamus, periaqueductal grey, raphé magnus and locus coeruleus were measured by radioimmunoassay in control and treated animals. There was no change in Met-enkephalin levels at either time point in any of the brain areas examined. © 1984.

Author-supplied keywords

  • Met-enkephalin
  • analgesia
  • nitrous oxide
  • pain pathways

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Authors

  • B. Morris

  • A. Livingston

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