An efficient route for commercially viable syntheses of furan- and thiophene-anellated β-hydroxychalcones

12Citations
Citations of this article
3Readers
Mendeley users who have this article in their library.
Get full text

Abstract

An efficient route for the syntheses of β-hydroxychalcones containing benzofuran and benzothiophene rings is described. Isoxazolines obtained from oxime-olefin cycloadditions were reduced under pressure to a mixture of products. Isoxazoles obtained from Claisen aroylation of an ester and subsequent acid cyclization, or from isoxazolines via DDQ-mediated dehydrogenation, were subjected to catalytic hydrogenation followed by hydrolysis to afford 1-phenyl-3-(benzofuran-5-yl)-1,3-diketone and 1-phenyl-3-(benzothiophene-5-yl)- 1,3-diketones in very good yields. © 2005 Elsevier Ltd. All rights reserved.

Cite

CITATION STYLE

APA

Yadav, P. P., Ahmad, G., & Maurya, R. (2005). An efficient route for commercially viable syntheses of furan- and thiophene-anellated β-hydroxychalcones. Tetrahedron Letters, 46(34), 5621–5624. https://doi.org/10.1016/j.tetlet.2005.06.111

Register to see more suggestions

Mendeley helps you to discover research relevant for your work.

Already have an account?

Save time finding and organizing research with Mendeley

Sign up for free