An efficient strategy for the synthesis of 5-hydroxyalkylbutan-4-olides from D-mannitol: Total synthesis of (-)-muricatacin

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Abstract

A general approach towards the synthesis of 5-hydroxyalkylbutan-4-olides from D-mannitol has been described. The approach has successfully been used for the total synthesis of (-)-muricatacin, an anti-tumor natural product. © 2002 Elsevier Science Ltd. All rights reserved.

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Chandrasekhar, M., Chandra, K. L., & Singh, V. K. (2002). An efficient strategy for the synthesis of 5-hydroxyalkylbutan-4-olides from D-mannitol: Total synthesis of (-)-muricatacin. Tetrahedron Letters, 43(15), 2773–2775. https://doi.org/10.1016/S0040-4039(02)00375-1

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