An efficient strategy for the synthesis of 5-hydroxyalkylbutan-4-olides from D-mannitol: Total synthesis of (-)-muricatacin

  • Chandrasekhar M
  • Chandra K
  • Singh V
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Abstract

A general approach towards the synthesis of 5-hydroxyalkylbutan-4-olides from D-mannitol has been described. The approach has successfully been used for the total synthesis of (-)-muricatacin, an anti-tumor natural product. © 2002 Elsevier Science Ltd. All rights reserved.

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Authors

  • M. Chandrasekhar

  • Kusum L. Chandra

  • Vinod K. Singh

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