Benzocyclohexane derivatives were prepared highly stereoselectively by the cyclic Friedel-Crafts reaction of 6-acetoxy-4-alkenyl arenes in moderate to excellent yields in TFA/HOAc (3:1). It was observed that the rate of the cyclization as well as the yields of products depend largely on the substituents of the allylic acetate moiety. © 2002 Elsevier Science Ltd. All rights reserved.
Ma, S., & Zhang, J. (2002). Efficient synthesis of benzocyclohexanes via intramolecular Friedel-Crafts reaction of halogen free 6-acetoxy-4-alkenyl arenes. Tetrahedron Letters, 43(18), 3435–3438. https://doi.org/10.1016/S0040-4039(02)00430-6