Enzymatic synthesis of nonracemic inherently chiral calix[4]arenes by lipase-catalysed transesterification

  • Browne J
  • McKervey M
  • Pitarch M
 et al. 
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Abstract

A lipase-catalysed transesterification to effect a desymmetrisation has been used to produce chiral calix[4]arene derivatives with enantiomer excesses (ee) of up to 100%.

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Authors

  • Julie K. Browne

  • M. Anthony McKervey

  • Miguel Pitarch

  • Julie A. Russell

  • Jeffrey S. Millership

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