Larvae of Drosophila were exposed to a range of concentrations of alpha particles from 3 to 318 mRad, and genetic effects measured in the wing-spot test. The results were positive, and evidence of a linear relationship between exposure and response observed. The induction of chromosome breakage is suggested by the significantly higher frequency of twin spots in the treated series compared with controls.
Pimentel, E., Zimmering, S., De La Rosa, M. E., Tavera, L., & Cruces, M. P. (1996). Evidence for an effect of exposure to low levels of alpha particle irradiation in larval cells of Drosophila as measured in the wing-spot test. Mutation Research - Fundamental and Molecular Mechanisms of Mutagenesis, 354(1), 139–142. https://doi.org/10.1016/0027-5107(96)00038-3