Familial syringomyelia: The first Japanese case and review of the literature

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Abstract

We reported on syringomyelia in a mother and her son. The mother was 74-year-old, who developed gait difficulty at the age of 54. The son, 47-year-old, developed the same symptoms at the age of 35. In the both cases, MRI revealed syringomyelia with Chiari malformation. Twenty-one families with syringomyelia have been reported. The existence of these families indicates that genetic factors may play in role to the pathogenesis of this disorder. © 2002 Elsevier Science B.V. All rights reserved.

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Yabe, I., Kikuchi, S., & Tashiro, K. (2002). Familial syringomyelia: The first Japanese case and review of the literature. Clinical Neurology and Neurosurgery, 105(1), 69–71. https://doi.org/10.1016/S0303-8467(02)00091-4

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