A fatal case of buflomedil (Fonzylane®) self-poisoning is presented. Drug identification and quantification in postmortem blood, urine and gastric contents was achieved by means of high pressure liquid chromatography with diode-array detection (HPLC/DAD). Blood concentration was 275 μg/ml, >70 times the usual therapeutic values. Toxicological results are discussed in the light of the existing literature. © 1995.
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