First hydroxamate inhibitors for carboxypeptidase A. N-acyl-N-hydroxy- β-phenylalanine S

  • Kim D
  • Jin Y
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Abstract

A series of N-acyl-N-hydroxy-β-Phe were designed, synthesized, and shown to have potent inhibitory activity for carboxypeptidase A (CPA). They are the first examples of CPA inhibitors having a hydroxamate functionality.

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Authors

  • D. H. Kim

  • Y. Jin

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