Free prolactin determinations in hyperprolactinemic men with suspicion of macroprolactinemia

  • Sapin R
  • Gasser F
  • Grucker D
  • 1

    Readers

    Mendeley users who have this article in their library.
  • 18

    Citations

    Citations of this article.

Abstract

Background: The Elecsys® prolactin (PRL) assay reacts more strongly with macroprolactin than the Centaur® PRL assay. We evaluated Elecsys direct and free PRL measurements vs. Centaur direct PRL measurements, in sera with and without macroprolactin. Methods: PRL was measured using Elecsys and Centaur direct assays and the Elecsys assay in the supernatant obtained after PEG precipitation (free PRL) in 34 sera from 34 hyperprolactinemic male subjects (Elecsys direct PRL > 434 mIU/l) classified, according to the PRL recovery after PEG precipitation, as: negative, i.e. without predominant macroprolactin (recovery %>50, n = 12), positive (recovery %

Author-supplied keywords

  • Hyperprolactinemia
  • Immunoassay
  • Macroprolactin
  • Polyethylene glycol precipitation
  • Prolactin

Get free article suggestions today

Mendeley saves you time finding and organizing research

Sign up here
Already have an account ?Sign in

Find this document

Authors

  • Rémy Sapin

  • Françoise Gasser

  • Daniel Grucker

Cite this document

Choose a citation style from the tabs below

Save time finding and organizing research with Mendeley

Sign up for free