Objectives: To examine the documentation tools used by hospital pharmacists for detection and management of drug-drug interactions (DDI) and to estimate their feelings to handle easily this issue in the context of the drug prescriptions analysis. Material and method: A questionnaire was sent to members of the Société Française de Pharmacie Clinique and hospital pharmacists included on the mailing list of the professional website of Association pour le Développement d'Internet en Pharmacie Hospitalière. Results: Two hundred and ninety-one pharmacists responded with an average of 16 years of professional experience. The Theriaque database and the Vidal dictionary appear as the most common and widely used as first line tool. More than three quarters of the participants feel comfortable or very comfortable to name the drugs involved in DDI and describe the effect. Respectively 76%, 75%, 59%, 72% and 57% of respondents expressed little or no ease to describe its time to onset, its intensity, to rate the potential severity, to specify the level of evidence supported by literature, and to propose the measures to be implemented. 68%, 56%, 30% and 21% of participants thought they might be more comfortable in the field of drug interactions through continuing education, by performing a more regular reading work, by the acquisition of software that automatically analyzes drug interactions and by acquiring an additional documentary tool respectively. Conclusion: The establishment of a continuing education program on management of drug-drug interactions in clinical routine is necessary. © 2012 Elsevier Masson SAS. All rights reserved.
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