GTP and cGMP both enhance, while cAMP depresses, the response to a furanose sugar of taste chemosensilla in the blowfly Protophormia terraenov ae

Abstract

1. 1. The stimulatory effect of a fructose (furanose sugar) solution on labellar taste chemosensilla in the blowfly Protophormia terraenovae is enhanced in the presence of GTP or cGMP. 2. 2. The increase in stimulating effectiveness due to cGMP is double with respect to that due to GTP. 3. 3. Chemosensillar responsiveness to the fructose solution is enhanced by the addition of an adenylate cyclase inhibitor, but is decreased by the addition of a phosphodiesterase inhibitor; these results are consistent with an inhibitory effect of cAMP. © 1989.