Increased serum triacylglycerol and cholesterol binding reserve in acute uremic rats

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Abstract

In acute uremic rats (24 h after bilateral nephrectomy, serum urea 280-300 mg/dl) the interface tension of the serum is significantly reduced. Serum levels of triacylglycerol are significantly elevated in uremia, whereas cholesterol levels do not show a significant alteration. The in vitro serum binding reserve for both, triacylglycerol and cholesterol is considerably enhanced. These results let suppose the presence of tenside-like substances in uremic serum which may be involved in disturbed triacylglycerol transport from the serum to the tissues and in development of uremic hypertriglyceridemia. © 1985, All rights reserved.

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Gottlob, R., Srour, A. N., Echsel, H., Molinari, E., Sogukoglu, T., Saghir, F., & Hohenegger, M. (1985). Increased serum triacylglycerol and cholesterol binding reserve in acute uremic rats. Experimental Pathology, 27(4), 249–252. https://doi.org/10.1016/S0232-1513(85)80066-9

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