Increased serum triacylglycerol and cholesterol binding reserve in acute uremic rats

  • Gottlob R
  • Srour A
  • Echsel H
 et al. 
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Abstract

In acute uremic rats (24 h after bilateral nephrectomy, serum urea 280-300 mg/dl) the interface tension of the serum is significantly reduced. Serum levels of triacylglycerol are significantly elevated in uremia, whereas cholesterol levels do not show a significant alteration. The in vitro serum binding reserve for both, triacylglycerol and cholesterol is considerably enhanced. These results let suppose the presence of tenside-like substances in uremic serum which may be involved in disturbed triacylglycerol transport from the serum to the tissues and in development of uremic hypertriglyceridemia. © 1985, All rights reserved.

Author-supplied keywords

  • acute uremia
  • lipoprotein electrophoresis
  • serum cholesterol binding reserve
  • serum interface tension
  • serum triacylglycerol binding reserve
  • uremic hypertriglyceridemia

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Authors

  • R. Gottlob

  • A. N. Srour

  • H. Echsel

  • E. Molinari

  • T. Sogukoglu

  • F. Saghir

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