Inhalation studies of Mt. St. Helens volcanic ash in animals. II. Lung function, biochemistry, and histology

23Citations
Citations of this article
5Readers
Mendeley users who have this article in their library.
Get full text

Abstract

Rats were exposed by inhalation to 9.4 mg/m3 size-fractionated volcanic ash for 5 days (2 hr/day) and examined for changes in pulmonary function and histology for periods of up to 1 year. Fine-mode volcanic ash, SO2, and a combination of ash and SO2 produced no observable effects in normal rats and rats with elastase-induced emphysema. However, there was a mild irritant response to SO2 which was not influenced by the volcanic ash. Rats injected intratracheally with fine-mode volcanic ash or saline showed no evidence of pulmonary alterations after 6 months. Those injected with coarse-mode volcanic ash showed minor pulmonary functional changes, histologically detectable alveolitis, and small increases in lung weight. In contrast, quartz-injected rats showed large alterations in pulmonary function, lung weight, hydroxyproline levels, and large areas of lung consolidation and fibrosis. © 1985.

Cite

CITATION STYLE

APA

Raub, J. A., Hatch, G. E., Mercer, R. R., Grady, M., & Hu, P. C. (1985). Inhalation studies of Mt. St. Helens volcanic ash in animals. II. Lung function, biochemistry, and histology. Environmental Research, 37(1), 72–83. https://doi.org/10.1016/0013-9351(85)90050-7

Register to see more suggestions

Mendeley helps you to discover research relevant for your work.

Already have an account?

Save time finding and organizing research with Mendeley

Sign up for free