Inhibitory effect of a mixture of herbal drugs (TJ-960, SK) on pentylenetetrazol-induced convulsions in El mice

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Abstract

TJ-960 is a spray-dried mixture of 9 herbal drugs. The convulsions of El mice induced by pentylenetetrazol (18 mg/kg) were completely inhibited by p.o. administration of TJ-960 at a daily dose of 1.0 g/kg both in 8-week-old and 4-week-old El mice. These findings suggest that TJ-960 has an inhibitory effect on the convulsions of this hereditary animal model of epilepsy. © 1988.

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Sugaya, E., Ishige, A., Sekiguchi, K., Iizuka, S., Sugimoto, A., Yuzurihara, M., & Hosoya, E. (1988). Inhibitory effect of a mixture of herbal drugs (TJ-960, SK) on pentylenetetrazol-induced convulsions in El mice. Epilepsy Research, 2(5), 337–339. https://doi.org/10.1016/0920-1211(88)90043-5

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