On the interaction between nicotine and cycloheximide

6Citations
Citations of this article
4Readers
Mendeley users who have this article in their library.
Get full text

Abstract

This study examined whether the nicotine-induced reversal of the amnestic effect of cycloheximide is due to an interaction between nicotine and cycloheximide on brain protein synthesis, and whether it involves the sites in brain that saturably bind [3H]nicotine. Nicotine did not reverse the cycloheximide-induced inhibition of protein synthesis, both in in vivo (intact animal) and in vitro (brain slice), suggesting that on-going protein synthesis is not necessarily involved in memory consolidation. The nicotine bindings sites were not affected by in vivo or in votro treatment with cycloheximide in the presence or absence of nicotine. © 1982.

Cite

CITATION STYLE

APA

Sershen, H., Reith, M. E. A., & Lajtha, A. (1982). On the interaction between nicotine and cycloheximide. Brain Research, 251(1), 183–185. https://doi.org/10.1016/0006-8993(82)91290-2

Register to see more suggestions

Mendeley helps you to discover research relevant for your work.

Already have an account?

Save time finding and organizing research with Mendeley

Sign up for free