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With a mucosa scraping of dog small intestine it was shown that isoglobotriaosylceramide (Galα1 → 3Galβ1 → 4Glcβ1 → 1Cer) was enriched in epithelial cells while the Forssman glycolipid (GalNAcα1 → 3GalNAcβ1 → 3Galα1 → 4Galβ1 → 4Glcβ1 → 1Cer) was found mainly in the non-epithelial part. The epithelial glycolipid was more hydroxylated in its ceramide than the Forssman glycolipid. These results supplement an earlier study on this tissue (Sung S.S. and Sweeley C.C. (1979) Biochim. Biophys. Acta 575, 295-298), posing a question on the biosynthetic interrelationship of the two glycolipids. © 1983.




Hansson, G. C., Karlsson, K. A., Larson, G., McKibbin, J. M., Strömberg, N., & Thurin, J. (1983). Isoglobotriaosylceramideand the forssman glycolipid of dog small intestine occupy separate tissue compartments and differ in ceramide composition. Biochimica et Biophysica Acta (BBA)/Lipids and Lipid Metabolism, 750(1), 214–216. https://doi.org/10.1016/0005-2760(83)90224-2

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