Isolation and identification of a specific and reversible inhibitor of starfish development

  • Tsuchimori N
  • Miyashiro S
  • Shibai H
 et al. 
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Abstract

An inhibitor of development of the starfish Asterina pectinifera was purified to homogeneity from a culture of the bacterium Bacillus subtilis, and was identified as adenosine. Adenosine at 6 μg/ml was shown to halt embryonic development specifically at the 256-cell stage when all the embryonic cells differentiate into epithelial cells. By returning treated embryos to normal seawater, they developed normally to the bipinnaria stage. © 1987.

Author-supplied keywords

  • Adenosine
  • Blastula
  • Starfish embryo, Bacillus subtilis)

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