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An inhibitor of development of the starfish Asterina pectinifera was purified to homogeneity from a culture of the bacterium Bacillus subtilis, and was identified as adenosine. Adenosine at 6 μg/ml was shown to halt embryonic development specifically at the 256-cell stage when all the embryonic cells differentiate into epithelial cells. By returning treated embryos to normal seawater, they developed normally to the bipinnaria stage. © 1987.




Tsuchimori, N., Miyashiro, S., Shibai, H., & Ikegami, S. (1987). Isolation and identification of a specific and reversible inhibitor of starfish development. FEBS Letters, 218(2), 205–208. https://doi.org/10.1016/0014-5793(87)81047-5

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