Large area high-resolution CCD-based X-ray detector for macromolecular crystallography

5Citations
Citations of this article
1Readers
Mendeley users who have this article in their library.
Get full text

Abstract

An X-ray detector system for macromolecular crystallography based on a large area charge-coupled device (CCD) sensor has been developed as part of a large research and development programme for advanced X-ray sensor technology, funded by industry and the Particle Physics and Astronomy Research Council (PPARC) in the UK. The prototype detector consists of two large area three-sides buttable charge-coupled devices (CCD 46-62 EEV), where the single CCD area is 55.3 mm×41.5 mm. Overall detector imaging area is easily extendable to 85 mm×110 mm. The detector consists of an optically coupled X-ray sensitive phosphor, skewed fibre-optic studs and CCDs. The crystallographic measurement requirements at synchrotron sources are met through a high spatial resolution (2048×1536 pixel array), high dynamic range (∼105), a fast readout (∼1 s), low noise (<10 e-1) and much reduced parallax error. Additionally, the prototype detector system has been optimised by increasing its efficiency at low X-ray energies for use at conventional lab sources. The system design of the prototype detector is discussed and the proposed method for crystallographic data processing is briefly outlined. © 2002 Elsevier Science B.V. All rights reserved.

Cite

CITATION STYLE

APA

Pokri, M., Allinson, N. M., Jorden, A. R., Cox, M. P., Marshall, A., Long, P. G., … Helliwell, J. R. (2002). Large area high-resolution CCD-based X-ray detector for macromolecular crystallography. In Nuclear Instruments and Methods in Physics Research, Section A: Accelerators, Spectrometers, Detectors and Associated Equipment (Vol. 477, pp. 166–171). https://doi.org/10.1016/S0168-9002(01)01881-2

Register to see more suggestions

Mendeley helps you to discover research relevant for your work.

Already have an account?

Save time finding and organizing research with Mendeley

Sign up for free