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Michael addition of various thiols to cyclic enones in presence of Li-X-type zeolite has been described. 13-Thiaprostaglandins have been synthesized in good yields using substituted hydroxycyclopentenone as the Michael acceptor and arylthiols as Michael donors. © 2004 Elsevier B.V. All rights reserved.




Shinde, P. D., Mahajan, V. A., Borate, H. B., Tillu, V. H., Bal, R., Chandwadkar, A., & Wakharkar, R. D. (2004). Li-X-type zeolite mediated Michael addition of thiols to cyclic enones and its application in the synthesis of 13-thiaprostaglandins. Journal of Molecular Catalysis A: Chemical, 216(1), 115–119. https://doi.org/10.1016/j.molcata.2004.02.008

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