Li-X-type zeolite mediated Michael addition of thiols to cyclic enones and its application in the synthesis of 13-thiaprostaglandins

  • Shinde P
  • Mahajan V
  • Borate H
 et al. 
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Michael addition of various thiols to cyclic enones in presence of Li-X-type zeolite has been described. 13-Thiaprostaglandins have been synthesized in good yields using substituted hydroxycyclopentenone as the Michael acceptor and arylthiols as Michael donors. © 2004 Elsevier B.V. All rights reserved.

Author-supplied keywords

  • Enones
  • Michael addition
  • Thiaprostaglandins
  • Thiols
  • Zeolites

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  • Popat D. Shinde

  • Vishal A. Mahajan

  • Hanumant B. Borate

  • Vasudha H. Tillu

  • Asha Chandwadkar

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