Membrane-associated phosphoinositidase C activity in Dictyostelium discoideum

  • Lundberg G
  • Newell P
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Abstract

Membrane-associated phosphoinositidase C activity has been identified in Dictyostelium discoideum using phosphatidylinositol 4,5-bisphosphate as exogenous substrate. Maximal activity was observed with 0.4 mM phosphatidylinositol 4,5-bisphosphate at pH 7.0. The enzyme was stimulated. by micromolar concentrations of free calcium with maximal activity at 100 μM. © 1990.

Author-supplied keywords

  • Dictyostelium discoideum
  • Membrane
  • Phosphatidylinositol 4,5-bisphosphate
  • Phosphoinositidase C
  • Signal transduction

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Authors

  • Gunilla A. Lundberg

  • Peter C. Newell

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