Mending human genes: A job for a lifetime

  • Cleaver J
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Abstract

I have described a number of milestones along a career of nearly 40 years in DNA repair. Most important was the discovery that the human disease xeroderma pigmentosum represented mutations in various components of nucleotide excision repair. This ushered in a new field of research involving numerous investigators and which continues to expand and amaze. © 2005 Elsevier B.V. All rights reserved.

Author-supplied keywords

  • Cockayne syndrome
  • Nucleotide excision repair
  • Postreplication repair
  • Radiobiology
  • Unscheduled DNA synthesis
  • Xeroderma pigmentosum

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Authors

  • James E. Cleaver

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