Microscale syntheses of anti-tumour platinum compounds labelled with191Pt

Citations of this article
Mendeley users who have this article in their library.
Get full text


Several compounds of platinum have been found to have significant anti-tumour activity and are in various stages of clinical trials. Four such compounds: cis-PtCl2(NH3)2, cis PtCl2(cyclopropylamine)2, cis,trans-PtCl2(OH)2(isopropylamine)2and cis-Pt(1,1-cyclobutanedicarboxylate)(NH3)2were synthesized with radioactive platinum-191 as a label for the study of animal organ distribution, patient blood clearance, urinary excretion and renal uptake and clearance. This paper describes the microscale synthesis of these compounds. Purification and quality control procedures are also described.




Baer, J., Harrison, R., McAuliffe, C. A., Zaki, A., Sharma, H. L., & Smith, A. G. (1985). Microscale syntheses of anti-tumour platinum compounds labelled with191Pt. International Journal of Applied Radiation and Isotopes, 36(3), 181–184. https://doi.org/10.1016/0020-708X(85)90064-X

Register to see more suggestions

Mendeley helps you to discover research relevant for your work.

Already have an account?

Save time finding and organizing research with Mendeley

Sign up for free