Moenomycin analogues with long-chain amine lipid parts from reductive aminations

  • Vogel S
  • Stembera K
  • Hennig L
 et al. 
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Abstract

From a moenomycin A glycolic aldehyde degradation product lacking the chromophore unit and most of the lipid part, a number of amines were prepared by reductive amination. Their interaction with artificial membranes as well as their transglycosylase inhibiting and antibiotic properties were studied. © 2001 Elsevier Science Ltd.

Author-supplied keywords

  • Antibiotics
  • Carbohydrates
  • Phospholipids
  • Reductive amination

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Authors

  • Stefan Vogel

  • Katherina Stembera

  • Lothar Hennig

  • Matthias Findeisen

  • Sabine Giesa

  • Peter Welzel

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