The mutagenic potentiator effect of chlorophyllin by the HGPRT assay

  • Negraes P
  • Jordão B
  • Vicentini V
 et al. 
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Abstract

Chlorophyllin, a sodium-copper salt derivative of chlorophyll-a and -b, was evaluated for antimutagenic activity against ethyl methane sulfonate by the hypoxanthin-guanine-phosphoribosyl transferase (HGPRT) assay. The results obtained suggest that this chlorophyllin can potentiate the mutagenicity of an alkylating agent which induces DNA damage. © 2003 Elsevier Ltd. All rights reserved.

Author-supplied keywords

  • CHO-K1 cells
  • Chlorophyllin
  • Mutagenicity
  • Potentiator effect
  • hgprt

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