The mutagenic potentiator effect of chlorophyllin by the HGPRT assay

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Abstract

Chlorophyllin, a sodium-copper salt derivative of chlorophyll-a and -b, was evaluated for antimutagenic activity against ethyl methane sulfonate by the hypoxanthin-guanine-phosphoribosyl transferase (HGPRT) assay. The results obtained suggest that this chlorophyllin can potentiate the mutagenicity of an alkylating agent which induces DNA damage. © 2003 Elsevier Ltd. All rights reserved.

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Negraes, P. D., Jordão, B. Q., Vicentini, V. E. P., & Mantovani, M. S. (2004). The mutagenic potentiator effect of chlorophyllin by the HGPRT assay. Toxicology in Vitro, 18(1), 147–149. https://doi.org/10.1016/j.tiv.2003.07.001

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