N4-hydroxycytidine: A mutagen specific for at to GC transitions

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N4-Hydroxycytidine is a mutagen of the base-analog type and of the products formed by treatment of cytidine with hydroxylamine. In this communication evidence is presented showing that, in contrast with other known base analogs, N4-hydroxycytidine results mainly, if not exclusively, in AT → GC transitional alterations in Escherichia coli K12. © 1980, All rights reserved.




Janion, C., & Glickman, B. W. (1980). N4-hydroxycytidine: A mutagen specific for at to GC transitions. Mutation Research - Fundamental and Molecular Mechanisms of Mutagenesis, 72(1), 43–47. https://doi.org/10.1016/0027-5107(80)90218-3

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