A new approach to the 2,5-diamino-5,6-dihydro-1H-pyrimidine-4-one derivatives: Synthesis of TAN-1057A/B and analogs

  • Zhang L
  • Xu L
  • Kim C
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Abstract

TAN-1057A/B has shown potent activity against MRSA. A new approach to the 2,5-diamino-5,6-dihydro-1H-pyrimidine-4-one derivatives has been developed. TAN-1057A/B and its analogs were efficiently synthesized using this new approach. © 2003 Published by Elsevier Ltd.

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Authors

  • Lijun Zhang

  • Lianhong Xu

  • Choung U. Kim

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