New bis(1-ferrocenylethyl)amine-derived monodentate phosphoramidite ligands for highly enantioselective copper-catalyzed 1,4-conjugate addition

  • Zou D
  • Duan Z
  • Hu X
 et al. 
  • 5

    Readers

    Mendeley users who have this article in their library.
  • 20

    Citations

    Citations of this article.

Abstract

A new family of chiral bis(1-ferrocenylethyl)amine-derived monodentate phosphoramidite ligands has been prepared and successfully applied in the Cu-catalyzed asymmetric 1,4-conjugate addition of diethylzinc to a variety of α,β-unsaturated compounds, in which up to 99% ee was obtained for nitroalkenes at -78 °C and >98% ee for cyclohexenone at -30 °C, comparable to or higher than those obtained with the most efficient monophosphoramidite ligands reported so far. © 2009 Elsevier Ltd. All rights reserved.

Get free article suggestions today

Mendeley saves you time finding and organizing research

Sign up here
Already have an account ?Sign in

Find this document

Authors

  • Dong Yun Zou

  • Zheng Chao Duan

  • Xiang Ping Hu

  • Zhuo Zheng

Cite this document

Choose a citation style from the tabs below

Save time finding and organizing research with Mendeley

Sign up for free