A new type of cytotoxic annonaceous acetogenin: Giganin from goniothalamus giganteus

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Abstract

A new cytotoxic Annonaceous acetogenin, giganin (1), was isolated from the bark of Goniothalamus giganteus (Annonaceae). This compound represents a new type of Annonaceous acetogenin lacking tetrahydrofuran or epoxide rings along the aliphatic chain, and its structure was elucidated by 1H and 13C NMR, MS, COSY, and single-relayed COSY. © 1993.

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Fang, X. ping, Song, R., Gu, Z. ming, Rieser, M. J., Miesbauer, L. R., Smith, D. L., & McLaughlin, J. L. (1993). A new type of cytotoxic annonaceous acetogenin: Giganin from goniothalamus giganteus. Bioorganic and Medicinal Chemistry Letters, 3(6), 1153–1156. https://doi.org/10.1016/S0960-894X(00)80305-4

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